Isabelle van Keulen is one of the few musicians who has established herself as both a violinist and violist on the major concert stages. As a soloist, she regularly works with major orchestras from all over the world under leading conductors.

She was Artistic Director of the Norwegian Chamber Orchestra for three years, has held a professorship for violin, viola and chamber music at the Lucerne University of Music since 2012 and has been Artistic Director of the Deutsche Kammerakademie Neuss am Rhein since 2017.

In chamber music, she was Artistic Director of the Delft Chamber Music Festival between 1997 and 2006. Numerous recordings reflect the breadth of her activities: her recordings span works from the Baroque and Classical periods to the 20th and 21st centuries, tango music and the Violin Concerto by Erkki-Sven Tüür dedicated to her. Most recently, she released the CD "Variations on Buenos Aires" in 2022. Concerts in 2024 will take her to the Elbphilharmonie Hamburg, the Konzerthaus, Vienna and Wigmore Hall, London, among others.